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A paralogous pair of mammalian host restriction factors form a critical host barrier against poxviru...

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxviru...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014516243

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

About this item

Full title

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2018-02, Vol.14 (2), p.e1006884-e1006884

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Host restriction factors constitute a formidable barrier for viral replication to which many viruses have evolved counter-measures. Human SAMD9, a tumor suppressor and a restriction factor for poxviruses in cell lines, is antagonized by two classes of poxvirus proteins, represented by vaccinia virus (VACV) K1 and C7. A paralog of SAMD9, SAMD9L, is...

Alternative Titles

Full title

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2014516243

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014516243

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1006884

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