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Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Deri...

Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Deri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014735347

Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures

About this item

Full title

Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-10, Vol.9 (10), p.e110324-e110324

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human motor neurons derived from embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are a potentially important tool for studying motor neuron survival and pathological cell death. However, their basic survival requirements remain poorly characterized. Here, we sought to optimize a robust survival assay and characterize their response...

Alternative Titles

Full title

Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2014735347

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014735347

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0110324

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