Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons
Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Amyloid aggregates of the protein α-synuclein (αS) called Lewy Bodies (LB) and Lewy Neurites (LN) are the pathological hallmark of Parkinson's disease (PD) and other synucleinopathies. We have previously shown that high extracellular αS concentrations can be toxic to cells and that neurons take up αS. Here we aimed to get more insight into the toxi...
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Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons
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TN_cdi_plos_journals_2017054016
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2017054016
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0193763
