Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Despite the important role of apolipoprotein E (apoE) secretion from astrocytes in brain lipid metabolism and the strong association of apoE4, one of the human apoE isoforms, with sporadic and late onset forms of Alzheimer's disease (AD) little is known about the regulation of astrocytic apoE. Utilizing annotated chemical libraries and a phenotypic...
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Full title
Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
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TN_cdi_plos_journals_2018656867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2018656867
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0194661
