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Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileu...

Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2024795928

Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileus

About this item

Full title

Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileus

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-04, Vol.13 (4), p.e0195516-e0195516

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

To explore the effects of abdominal surgery and interleukin-1 signaling on antimicrobial defense in a model of postoperative ileus.
C57BL/6 and Interleukin-1 receptor type I (IL-1R1) deficient mice underwent intestinal manipulation to induce POI. Expression of mucosal IL-1α, IL-1β and IL-1R1 and several antimicrobial peptides and enzymes were me...

Alternative Titles

Full title

Intestinal manipulation affects mucosal antimicrobial defense in a mouse model of postoperative ileus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2024795928

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2024795928

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0195516

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