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Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2025697009

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

About this item

Full title

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

Publisher

United States: Public Library of Science

Journal title

PLoS medicine, 2018-03, Vol.15 (3), p.e1002535

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Despite repeated outbreaks, in particular the devastating 2014-2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD). Among the drug candidates is the broad-spectrum polymerase inhibitor favipiravir, which showed a good tolerance profile in patients with EVD (JIKI trial) but did not demonstrate a stron...

Alternative Titles

Full title

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2025697009

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2025697009

Other Identifiers

ISSN

1549-1676,1549-1277

E-ISSN

1549-1676

DOI

10.1371/journal.pmed.1002535

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