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HSV-1-induced disruption of transcription termination resembles a cellular stress response but selec...

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2025706764

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes

About this item

Full title

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2018-03, Vol.14 (3), p.e1006954-e1006954

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lytic herpes simplex virus 1 (HSV-1) infection triggers disruption of transcription termination (DoTT) of most cellular genes, resulting in extensive intergenic transcription. Similarly, cellular stress responses lead to gene-specific transcription downstream of genes (DoG). In this study, we performed a detailed comparison of DoTT/DoG transcriptio...

Alternative Titles

Full title

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2025706764

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2025706764

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1006954

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