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Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic...

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2043736500

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches

About this item

Full title

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-05, Vol.13 (5), p.e0198145-e0198145

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Sequencing of Streptomyces genomes has revealed they harbor a high number of biosynthesis gene cluster (BGC), which uncovered their enormous potentiality to encode specialized metabolites. However, these metabolites are not usually produced under standard laboratory conditions. In this manuscript we report the activation of BGCs for antimycins, car...

Alternative Titles

Full title

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2043736500

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2043736500

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0198145

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