Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access
Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
D-amino acid oxidase (DAAO) degrades D-amino acids to produce α-ketoacids, hydrogen peroxide and ammonia. DAAO has often been investigated and engineered for industrial and clinical applications. We combined information from literature with a detailed analysis of the structure to engineer mammalian DAAOs. The structural analysis was complemented wi...
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Full title
Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access
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TN_cdi_plos_journals_2055917121
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2055917121
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0198990