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Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibrobl...

Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibrobl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2057888246

Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts

About this item

Full title

Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-06, Vol.13 (6), p.e0199412-e0199412

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Although small intestinal epithelial stem cells form crypts when using intestinal culture conditions, colon stem cells usually form colonospheres. Colon mesenchymal cell feeder layers can stimulate colon crypts to form organoids and produce crypts. We have investigated whether conditioned medium from colon mesenchymal cells can also stimulate colon...

Alternative Titles

Full title

Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2057888246

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2057888246

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0199412

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