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B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in...

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2059528671

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis

About this item

Full title

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-06, Vol.13 (6), p.e0199694-e0199694

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune encephalomyelitis (EAE), a murine model of MS, we have previously shown that mice in which B cells are the only MHCII-expressing antigen present...

Alternative Titles

Full title

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2059528671

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2059528671

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0199694

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