A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular l...
A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Bacterial efflux pumps transport small molecules from the cytoplasm or periplasm outside the cell. Efflux pump activity is typically increased in multi-drug resistant (MDR) pathogens; chemicals that inhibit efflux pumps may have potential for antibiotic development. Using an in-cell screen, we identified three efflux pump modulators (EPMs) from a d...
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Full title
A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load
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TN_cdi_plos_journals_2070854110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2070854110
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007115
