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Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and im...

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and im...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2082087928

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing

About this item

Full title

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-07, Vol.13 (7), p.e0197333-e0197333

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Circulating tumor-derived cell-free DNA (ctDNA) enables non-invasive diagnosis, monitoring, and treatment susceptibility testing in human cancers. However, accurate detection of variant alleles, particularly during untargeted searches, remains a principal obstacle to widespread application of cell-free DNA in clinical oncology. In this study, isola...

Alternative Titles

Full title

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2082087928

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2082087928

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0197333

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