Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas,...
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Gelatinase B/matrix metalloproteinase-9 (MMP-9) triggers multiple sclerosis (MS) and the animal model of experimental autoimmune encephalomyelitis (EAE) by the breakdown of the blood-brain barrier. Interestingly, MMP-9 is beneficial in systemic autoimmunity caused by Fas-deficiency. Fas-deficient (faslpr) and Fas-ligand-deficient mice are protected...
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Full title
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis
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TN_cdi_plos_journals_2115232515
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2115232515
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0197944
