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Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes see...

Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes see...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2115234221

Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

About this item

Full title

Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-10, Vol.13 (10), p.e0204967

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in host-microbial interactions and epithelial homeostasis. The ramifications of eliminating Paneth cell function on...

Alternative Titles

Full title

Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2115234221

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2115234221

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0204967

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