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Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration...

Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2117860413

Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

About this item

Full title

Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-10, Vol.13 (10), p.e0204941-e0204941

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The results from cross sectional and longitudinal studies show that periodontitis is closely associated with cognitive impairment (CI) and Alzhemer's Disease (AD). Further, studies using animal model of periodontitis and human post-mortem brain tissues from subjects with AD strongly suggest that a gram-negative periodontal pathogen, Porphyromonas g...

Alternative Titles

Full title

Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2117860413

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2117860413

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0204941

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