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Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal...

Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2150531268

Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting

About this item

Full title

Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-12, Vol.13 (12), p.e0208122-e0208122

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Delivering therapeutics across the blood-brain barrier (BBB) for treating central nervous system (CNS) diseases is one of the biggest challenges today as the BBB limits the uptake of molecules greater than 500 Da into the CNS. Here we describe a novel trans-nasal mucosal drug delivery as an alternative to the intranasal drug delivery to overcome it...

Alternative Titles

Full title

Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2150531268

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2150531268

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0208122

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