In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization o...
In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
G protein coupled receptors (GPCRs) are central players in recognizing a variety of stimuli to mediate diverse cellular responses. This myriad of functions is accomplished by their modular interactions with downstream intracellular transducers, such as heterotrimeric G proteins and arrestins. Assembling a specific GPCR-G protein pair as a purified...
Alternative Titles
Full title
In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2165054095
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2165054095
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0210131
