A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its in...
A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Endotoxin, a component of the outer membrane of Gram-negative bacteria, has been extensively studied as a stimulator of the innate immune response. However, the temporal aspects and exposure-response relationship of endotoxin and resulting cytokine induction and tolerance development is less well defined. The aim of this work was to establish an in...
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A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6
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TN_cdi_plos_journals_2185149951
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2185149951
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0211981
