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Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 f...

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 f...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2219679751

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish

About this item

Full title

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-05, Vol.14 (5), p.e0216159-e0216159

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Glycine receptors (GlyRs) are ligand-gated chloride channels mediating inhibitory neurotransmission in the brain stem and spinal cord. They function as pentamers composed of alpha and beta subunits for which 5 genes have been identified in human (GLRA1, GLRA2, GLRA3, GLRA4, GLRB). Several in vitro studies showed that the pentameric subtype composit...

Alternative Titles

Full title

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2219679751

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2219679751

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0216159

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