ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole
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Author / Creator
Lang, Qin , Yidong, Xie , Xueguang, Zhang , Sixian, Wu , Wenming, Xu and Tao, Zuo
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Chronic inflammation is a typical characteristic of polycystic ovary syndrome (PCOS), in which, tumor necrosis factor (TNF)-α plays an important role. We investigated whether anti-TNF-α therapy can alleviate the core phenotypes of PCOS. In pubertal female Wistar rats, release pellets of letrozole (LET) were administered continuously for 90 days to...
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Full title
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole
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Record Identifier
TN_cdi_plos_journals_2236173230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2236173230
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0217495
