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Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brai...

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brai...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2242104638

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

About this item

Full title

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-06, Vol.14 (6), p.e0217765-e0217765

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Of the 108 Schizophrenia (SZ) risk-loci discovered through genome-wide association studies (GWAS), 96 are not altering the sequence of any protein. Evidence linking non-coding risk-SNPs and genes may be established using expression quantitative trait loci (eQTL). However, other approaches such allelic expression quantitative trait loci (aeQTL) also...

Alternative Titles

Full title

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2242104638

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2242104638

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0217765

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