Log in to save to my catalogue

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across euk...

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across euk...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249755042

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

About this item

Full title

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2018-08, Vol.16 (8), p.e2006357-e2006357

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

HAPLESS2 (HAP2) is a broadly conserved, gamete-expressed transmembrane protein that was shown recently to be structurally homologous to viral class II fusion proteins, which initiate fusion with host cells via insertion of fusion loops into the host membrane. However, the functional conformation of the HAP2 fusion loops has remained unknown, as the...

Alternative Titles

Full title

Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2249755042

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249755042

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.2006357

How to access this item