Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across euk...
Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes
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United States: Public Library of Science
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English
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United States: Public Library of Science
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HAPLESS2 (HAP2) is a broadly conserved, gamete-expressed transmembrane protein that was shown recently to be structurally homologous to viral class II fusion proteins, which initiate fusion with host cells via insertion of fusion loops into the host membrane. However, the functional conformation of the HAP2 fusion loops has remained unknown, as the...
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Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes
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TN_cdi_plos_journals_2249755042
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249755042
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1545-7885,1544-9173
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1545-7885
DOI
10.1371/journal.pbio.2006357