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Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adul...

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adul...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249961065

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

About this item

Full title

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2019-02, Vol.17 (2), p.e3000134

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Microglia are resident immune cells that play critical roles in maintaining the normal physiology of the central nervous system (CNS). Remarkably, microglia have an intrinsic capacity to repopulate themselves after acute ablation. However, the underlying mechanisms that drive such restoration remain elusive. Here, we characterized microglial repopu...

Alternative Titles

Full title

Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2249961065

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249961065

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000134

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