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Review: Precision medicine and driver mutations: Computational methods, functional assays and confor...

Review: Precision medicine and driver mutations: Computational methods, functional assays and confor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2250643421

Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers

About this item

Full title

Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2019-03, Vol.15 (3), p.e1006658-e1006658

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

At the root of the so-called precision medicine or precision oncology, which is our focus here, is the hypothesis that cancer treatment would be considerably better if therapies were guided by a tumor's genomic alterations. This hypothesis has sparked major initiatives focusing on whole-genome and/or exome sequencing, creation of large databases, a...

Alternative Titles

Full title

Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2250643421

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2250643421

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1006658

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