Nucleosome positions establish an extended mutation signature in melanoma
Nucleosome positions establish an extended mutation signature in melanoma
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Ultraviolet (UV) light-induced mutations are unevenly distributed across skin cancer genomes, but the molecular mechanisms responsible for this heterogeneity are not fully understood. Here, we assessed how nucleosome structure impacts the positions of UV-induced mutations in human melanomas. Analysis of mutation positions from cutaneous melanomas w...
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Nucleosome positions establish an extended mutation signature in melanoma
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TN_cdi_plos_journals_2251022719
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251022719
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007823