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Nucleosome positions establish an extended mutation signature in melanoma

Nucleosome positions establish an extended mutation signature in melanoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251022719

Nucleosome positions establish an extended mutation signature in melanoma

About this item

Full title

Nucleosome positions establish an extended mutation signature in melanoma

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2018-11, Vol.14 (11), p.e1007823-e1007823

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Ultraviolet (UV) light-induced mutations are unevenly distributed across skin cancer genomes, but the molecular mechanisms responsible for this heterogeneity are not fully understood. Here, we assessed how nucleosome structure impacts the positions of UV-induced mutations in human melanomas. Analysis of mutation positions from cutaneous melanomas w...

Alternative Titles

Full title

Nucleosome positions establish an extended mutation signature in melanoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251022719

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251022719

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1007823

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