Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor...
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
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Author / Creator
Song, Wenfei , Gui, Miao , Wang, Xinquan and Xiang, Ye
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to postfusion conformation transition. Here, we report the structure of the SARS-CoV S glycoprotein i...
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Full title
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
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Record Identifier
TN_cdi_plos_journals_2251084685
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251084685
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007236