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A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate bind...

A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate bind...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251085247

A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism

About this item

Full title

A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2018-08, Vol.14 (8), p.e1007190-e1007190

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Enterovirus 71 (EV71) causes hand, foot and mouth disease, a mild and self-limited illness that is sometimes associated with severe neurological complications. EV71 neurotropic determinants remain ill-defined to date. We previously identified a mutation in the VP1 capsid protein (L97R) that was acquired over the course of a disseminated infection i...

Alternative Titles

Full title

A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251085247

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251085247

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007190

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