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Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thromb...

Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thromb...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251140747

Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage

About this item

Full title

Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007625-e1007625

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Dengue virus (DENV) infection, the most common mosquito-transmitted viral infection, can cause a range of diseases from self-limiting dengue fever to life-threatening dengue hemorrhagic fever and shock syndrome. Thrombocytopenia is a major characteristic observed in both mild and severe dengue disease and is significantly correlated with the progre...

Alternative Titles

Full title

Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251140747

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251140747

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007625

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