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PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of...

PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2262504509

PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of prion-infected mice immunotolerant to treatment

About this item

Full title

PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of prion-infected mice immunotolerant to treatment

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-07, Vol.14 (7), p.e0219995-e0219995

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Prion diseases are members of neurodegenerative protein misfolding diseases (NPMDs) that include Alzheimer's, Parkinson's and Huntington diseases, amyotrophic lateral sclerosis, tauopathies, traumatic brain injuries, and chronic traumatic encephalopathies. No known therapeutics extend survival or improve quality of life of humans afflicted with pri...

Alternative Titles

Full title

PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of prion-infected mice immunotolerant to treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2262504509

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2262504509

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0219995

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