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Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Lito...

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Lito...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2262873166

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

About this item

Full title

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2019-01, Vol.13 (1), p.e0006320

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Flubendazole (FBZ) is highly efficacious against filarial nematodes after parenteral administration and presents a promising macrofilaricidal drug candidate for the elimination of onchocerciasis and other filariae. In the present study the efficacy of a newly developed bioavailable amorphous solid dispersion (ASD) oral formulation of FBZ was invest...

Alternative Titles

Full title

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2262873166

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2262873166

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0006320

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