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Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional...

Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2275482972

Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection

About this item

Full title

Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2019-07, Vol.15 (7), p.e1007935-e1007935

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Plasmacytoid dendritic cells (pDCs) are "natural" interferon α (IFNα)-producing cells. Despite their importance to antiviral defense, autoimmunity, and ischemic liver graft injury, because DC subsets are rare and heterogeneous, basic questions about liver pDC function and capacity to make cytokines remain unanswered. Previous investigations failed...

Alternative Titles

Full title

Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2275482972

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2275482972

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007935

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