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Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized solub...

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized solub...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2275483568

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

About this item

Full title

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2019-07, Vol.15 (7), p.e1007920-e1007920

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The HIV-1 envelope glycoprotein (Env) trimer is located on the surface of the virus and is the target of broadly neutralizing antibodies (bNAbs). Recombinant native-like soluble Env trimer mimetics, such as SOSIP trimers, have taken a central role in HIV-1 vaccine research aimed at inducing bNAbs. We therefore performed a direct and thorough compar...

Alternative Titles

Full title

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2275483568

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2275483568

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1007920

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