False-negative errors in next-generation sequencing contribute substantially to inconsistency of mut...
False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
More than 11,000 laboratories and companies developed their own next-generation sequencing (NGS) for screening and diagnosis of various diseases including cancer. Although inconsistencies of mutation calls as high as 43% in databases such as GDSC (Genomics of Drug Sensitivity in Cancer) and CCLE (Cancer Cell Line Encyclopedia) have been reported, n...
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Full title
False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases
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TN_cdi_plos_journals_2289562877
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2289562877
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0222535
