Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 comp...
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex
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Author / Creator
Xu, Gang , Xia, Zhangchuan , Deng, Feiyan , Liu, Lin , Wang, Qiming , Yu, Yi , Wang, Fubing , Zhu, Chengliang , Liu, Weiyong , Cheng, Zhikui , Zhu, Ying , Zhou, Li , Zhang, Yi , Lu, Mengji and Liu, Shi
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The galectin 3 binding protein (LGALS3BP, also known as 90K) is a ubiquitous multifunctional secreted glycoprotein originally identified in cancer progression. It remains unclear how 90K functions in innate immunity during viral infections. In this study, we found that viral infections resulted in elevated levels of 90K. Further studies demonstrate...
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Full title
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex
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TN_cdi_plos_journals_2291478514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2291478514
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008002