The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by a...
The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors
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Author / Creator
Cao, Pan , Luo, Wei-Wei , Li, Chen , Tong, Zhen , Zheng, Zhou-Qin , Zhou, Lu , Xiong, Yong and Li, Shu
Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Recognition of viral RNA by the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), including RIG-I and MDA5, initiates innate antiviral responses. Although regulation of RLR-mediated signal transduction has been extensively investigated, how the recognition of viral RNA by RLRs is regulated remains enigmatic. In this study, we identified...
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Full title
The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors
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TN_cdi_plos_journals_2291478899
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2291478899
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007983