Discovery of novel West Nile Virus protease inhibitor based on isobenzonafuranone and triazolic deri...
Discovery of novel West Nile Virus protease inhibitor based on isobenzonafuranone and triazolic derivatives of eugenol and indan-1,3-dione scaffolds
About this item
Full title
Author / Creator
de Oliveira, André S , Gazolla, Poliana A R , Oliveira, Ana Flávia C da S , Pereira, Wagner L , de S Viol, Lívia C , Maia, Angélica F da S , Santos, Edjon G , da Silva, Ítalo E P , Mendes, Tiago A de Oliveira , da Silva, Adalberto M , Dias, Roberto S , da Silva, Cynthia C , Polêto, Marcelo D , Teixeira, Róbson R and de Paula, Sergio O
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The West Nile Virus (WNV) NS2B-NS3 protease is an attractive target for the development of therapeutics against this arboviral pathogen. In the present investigation, the screening of a small library of fifty-eight synthetic compounds against the NS2-NB3 protease of WNV is described. The following groups of compounds were evaluated: 3-(2-aryl-2-oxo...
Alternative Titles
Full title
Discovery of novel West Nile Virus protease inhibitor based on isobenzonafuranone and triazolic derivatives of eugenol and indan-1,3-dione scaffolds
Authors, Artists and Contributors
Author / Creator
Gazolla, Poliana A R
Oliveira, Ana Flávia C da S
Pereira, Wagner L
de S Viol, Lívia C
Maia, Angélica F da S
Santos, Edjon G
da Silva, Ítalo E P
Mendes, Tiago A de Oliveira
da Silva, Adalberto M
Dias, Roberto S
da Silva, Cynthia C
Polêto, Marcelo D
Teixeira, Róbson R
de Paula, Sergio O
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2298566815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2298566815
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0223017
