Development of a new largely scalable in vitro prion propagation method for the production of infect...
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies
About this item
Full title
Author / Creator
Eraña, Hasier , Charco, Jorge M. , Di Bari, Michele A. , Díaz-Domínguez, Carlos M. , López-Moreno, Rafael , Vidal, Enric , González-Miranda, Ezequiel , Pérez-Castro, Miguel A. , García-Martínez, Sandra , Bravo, Susana , Fernández-Borges, Natalia , Geijo, Mariví , D’Agostino, Claudia , Garrido, Joseba , Bian, Jifeng , König, Anna , Uluca-Yazgi, Boran , Sabate, Raimon , Khaychuk, Vadim , Vanni, Ilaria , Telling, Glenn C. , Heise, Henrike , Nonno, Romolo , Requena, Jesús R. and Castilla, Joaquín
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long hindered due to certain particularities of these proteinaceous pathogens. Difficulties related to their purification from brain homogenates of dise...
Alternative Titles
Full title
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies
Authors, Artists and Contributors
Author / Creator
Charco, Jorge M.
Di Bari, Michele A.
Díaz-Domínguez, Carlos M.
López-Moreno, Rafael
Vidal, Enric
González-Miranda, Ezequiel
Pérez-Castro, Miguel A.
García-Martínez, Sandra
Bravo, Susana
Fernández-Borges, Natalia
Geijo, Mariví
D’Agostino, Claudia
Garrido, Joseba
Bian, Jifeng
König, Anna
Uluca-Yazgi, Boran
Sabate, Raimon
Khaychuk, Vadim
Vanni, Ilaria
Telling, Glenn C.
Heise, Henrike
Nonno, Romolo
Requena, Jesús R.
Castilla, Joaquín
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2314933907
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2314933907
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008117
