Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma...
Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Cholangiocarcinoma (CCA), a malignant tumor originating in the biliary tract, is well known to be associated with adverse clinical outcomes and high mortality rates due to the lack of effective therapy. Evasion of apoptosis is considered a key contributor to therapeutic success and chemotherapy resistance in CCA, highlighting the need for novel the...
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Full title
Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
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TN_cdi_plos_journals_2334681941
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2334681941
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0227454
