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ArticlesPeer ReviewedFull Text
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
Author / Creator:Zhao, Jie ; Jitkaew, Siriporn ; Cai, Zhenyu ; Choksi, Swati ; Li, Qiuning ; Luo, Ji ; Liu, Zheng-Gang
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5322-5327
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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
Author / Creator:Cai, Zhenyu ; Jitkaew, Siriporn ; Zhao, Jie ; Chiang, Hsueh-Cheng ; Choksi, Swati ; Liu, Jie ; Ward, Yvona ; Wu, Ling-gang ; Liu, Zheng-Gang
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2014-01, Vol.16 (1), p.55-65
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Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma
Author / Creator:Lomphithak, Thanpisit ; Akara-amornthum, Perawatt ; Murakami, Keigo ; Hashimoto, Masatoshi ; Usubuchi, Hajime ; Iwabuchi, Erina ; Unno, Michiaki ; Cai, Zhenyu ; Sasano, Hironobu ; Jitkaew, Siriporn
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-06, Vol.11 (1), p.11743-11743, Article 11743
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CDK4/6 inhibitors upregulate cIAP1/2, and Smac mimetic LCL161 enhances their antitumor effects in cholangiocarcinoma cells
Author / Creator:Menapree, Pimchanok ; Duangthim, Nattaya ; Sae-Fung, Apiwit ; Sonkaew, Sasiprapa ; Jitkaew, Siriporn
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-02, Vol.15 (1), p.6826-16, Article 6826
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Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
Author / Creator:Akara-amornthum, Perawatt ; Lomphithak, Thanpisit ; Choksi, Swati ; Tohtong, Rutaiwan ; Jitkaew, Siriporn
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0227454-e0227454
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Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis
Author / Creator:Zhao, Yaxing ; Wang, Qingsong ; Zhu, Jing ; Cai, Jin ; Feng, Xiaona ; Song, Qianqian ; Jiang, Hui ; Ren, Wenqing ; He, Yuan ; Wang, Ping ; Feng, Du ; Yu, Jianqiang ; Liu, Yue ; Wu, Qihui ; Jitkaew, Siriporn ; Cai, Zhenyu
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2024-10, Vol.15 (10), p.764-17, Article 764
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Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling
Author / Creator:Shen, Hua ; Yu, Xiaobo ; Yang, Fengming ; Zhang, Zhihua ; Shen, Jianxin ; Sun, Jin ; Choksi, Swati ; Jitkaew, Siriporn ; Shu, Yongqian
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2016-08, Vol.12 (8), p.e1006244-e1006244
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Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA damage and contributes to toxic side effects of chemotherapy
Author / Creator:Wang, Fang ; Li, Kaiying ; Wang, Wensheng ; Jiang, Hui ; He, Jiangping ; Cai, Jin ; Ren, Wenqing ; Zhao, Yaxing ; Song, Qianqian ; He, Yuan ; Ma, Yanlei ; Feng, Xiaona ; Liu, Yue ; Yu, Jianqiang ; Jitkaew, Siriporn ; Ma, Dan ; Cai, Zhenyu
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2024-10, Vol.15 (10), p.779-14, Article 779
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Prognostic significance and response to immune checkpoint inhibitors of RIPK3, MLKL and necroptosis in non-small cell lung cancer
Author / Creator:Duangthim, Nattaya ; Lomphithak, Thanpisit ; Saito-Koyama, Ryoko ; Miki, Yasuhiro ; Inoue, Chihiro ; Sato, Ikuro ; Miyauchi, Eisaku ; Abe, Jiro ; Sasano, Hironobu ; Jitkaew, Siriporn
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-09, Vol.14 (1), p.21625-17, Article 21625
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The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited
Author / Creator:Xu, Qing ; Jitkaew, Siriporn ; Choksi, Swati ; Kadigamuwa, Chamila ; Qu, Jianhui ; Choe, Moran ; Jang, Jonathan ; Liu, Chengyu ; Liu, Zheng-gang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.425-15, Article 425
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ArticlesPeer ReviewedFull Text
Correction: Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis
Author / Creator:Zhao, Yaxing ; Wang, Qingsong ; Zhu, Jing ; Cai, Jin ; Feng, Xiaona ; Song, Qianqian ; Jiang, Hui ; Ren, Wenqing ; He, Yuan ; Wang, Ping ; Feng, Du ; Yu, Jianqiang ; Liu, Yue ; Wu, Qihui ; Jitkaew, Siriporn ; Cai, Zhenyu
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2025-05, Vol.16 (1), p.375-1, Article 375
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Correction: Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA damage and contributes to toxic side effects of chemotherapy
Author / Creator:Wang, Fang ; Li, Kaiying ; Wang, Wensheng ; Jiang, Hui ; He, Jiangping ; Cai, Jin ; Ren, Wenqing ; Zhao, Yaxing ; Song, Qianqian ; He, Yuan ; Ma, Yanlei ; Feng, Xiaona ; Liu, Yue ; Yu, Jianqiang ; Jitkaew, Siriporn ; Ma, Dan ; Cai, Zhenyu
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2025-05, Vol.16 (1), p.406-1, Article 406
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ArticlesPeer ReviewedFull Text
ACSL3 is an unfavorable prognostic marker in cholangiocarcinoma patients and confers ferroptosis resistance in cholangiocarcinoma cells
Author / Creator:Sae-Fung, Apiwit ; Vinayavekhin, Nawaporn ; Fadeel, Bengt ; Jitkaew, Siriporn
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2024-12, Vol.8 (1), p.284-14, Article 284
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RTK25: A Comprehensive Molecular Profiling Strategy in Cholangiocarcinoma Using an Integrated Bioinformatics Approach
Author / Creator:Balasubramanian, Brinda ; Venkatraman, Simran ; Janvilisri, Tavan ; Suthiphongchai, Tuangporn ; Jitkaew, Siriporn ; Sripa, Jittiyawadee ; Tohtong, Rutaiwan
Publisher:Basel: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-09, Vol.14 (9), p.898
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ArticlesPeer ReviewedFull Text
Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma
Author / Creator:Lomphithak, Thanpisit ; Choksi, Swati ; Mutirangura, Apiwat ; Tohtong, Rutaiwan ; Tencomnao, Tewin ; Usubuchi, Hajime ; Unno, Michiaki ; Sasano, Hironobu ; Jitkaew, Siriporn
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2020-10, Vol.18 (1), p.161-161, Article 161
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Necroptosis inhibitors: mechanisms of action and therapeutic potential
Author / Creator:Zhou, Yingbo ; Cai, Zhangtao ; Zhai, Yijia ; Yu, Jintao ; He, Qiujing ; He, Yuan ; Jitkaew, Siriporn ; Cai, Zhenyu
Publisher:New York: Springer US
Journal title:Apoptosis (London), 2024-02, Vol.29 (1-2), p.22-44
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Natural Flavonoids Quercetin and Kaempferol Targeting G2/M Cell Cycle-Related Genes and Synergize with Smac Mimetic LCL-161 to Induce Necroptosis in Cholangiocarcinoma Cells
Author / Creator:Lomphithak, Thanpisit ; Jaikla, Patthorn ; Sae-Fung, Apiwit ; Sonkaew, Sasiprapa ; Jitkaew, Siriporn
Publisher:Switzerland: MDPI AG
Journal title:Nutrients, 2023-07, Vol.15 (14), p.3090
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Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-[alpha] and chemotherapeutic gemcitabine-induced necroptosis
Author / Creator:Akara-amornthum, Perawatt ; Lomphithak, Thanpisit ; Choksi, Swati ; Tohtong, Rutaiwan ; Jitkaew, Siriporn ; Lebedeva, Irina V
Publisher:Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0227454
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Erratum: Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
Author / Creator:Cai, Zhenyu ; Jitkaew, Siriporn ; Zhao, Jie ; Chiang, Hsueh-Cheng ; Choksi, Swati ; Liu, Jie ; Ward, Yvona ; Wu, Ling-gang ; Liu, Zheng-Gang
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2014-02, Vol.16 (2), p.200-200
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ArticlesPeer ReviewedFull Text
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
Author / Creator:Cai, Zhenyu ; Jitkaew, Siriporn ; Zhao, Jie ; Chiang, Hsueh-Cheng ; Choksi, Swati ; Liu, Jie ; Ward, Yvona ; Wu, Ling-gang ; Liu, Zheng-Gang
Publisher:Nature Publishing Group
Journal title:Nature cell biology, 2014-02, Vol.16 (2)
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Showing 1 to 20 of 20 results

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

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Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma

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CDK4/6 inhibitors upregulate cIAP1/2, and Smac mimetic LCL161 enhances their antitumor effects in cholangiocarcinoma cells

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Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis

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Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis

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Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling

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Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA damage and contributes to toxic side effects of chemotherapy

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Prognostic significance and response to immune checkpoint inhibitors of RIPK3, MLKL and necroptosis in non-small cell lung cancer

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The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited

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Correction: Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis

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Correction: Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA damage and contributes to toxic side effects of chemotherapy

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ACSL3 is an unfavorable prognostic marker in cholangiocarcinoma patients and confers ferroptosis resistance in cholangiocarcinoma cells

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RTK25: A Comprehensive Molecular Profiling Strategy in Cholangiocarcinoma Using an Integrated Bioinformatics Approach

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Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma

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Necroptosis inhibitors: mechanisms of action and therapeutic potential

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Natural Flavonoids Quercetin and Kaempferol Targeting G2/M Cell Cycle-Related Genes and Synergize with Smac Mimetic LCL-161 to Induce Necroptosis in Cholangiocarcinoma Cells

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Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-[alpha] and chemotherapeutic gemcitabine-induced necroptosis

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Erratum: Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

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