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Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2355997875

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

About this item

Full title

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2020-01, Vol.16 (1), p.e1008277-e1008277

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, trimeric, and hexameric protein contacts. Among retroviruses the inter- and intra-hexamer contacts dif...

Alternative Titles

Full title

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2355997875

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2355997875

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1008277

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