Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft mo...
Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Truncated tissue factor (tTF) retargeted by NGR-peptides to aminopeptidase N (CD13) in tumor vasculature is effective in experimental tumor therapy. tTF-NGR induces tumor growth inhibition in a variety of human tumor xenografts of different histology. To improve on the therapeutic efficacy we have combined tTF-NGR with radiotherapy.
Serum-stimul...
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Full title
Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma
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TN_cdi_plos_journals_2360073649
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2360073649
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0229271
