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Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus inf...

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus inf...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2377705357

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells

About this item

Full title

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2020-02, Vol.16 (2), p.e1008319-e1008319

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in children worldwide. Sirtuin 1 (SIRT1), a NAD+ dependent deacetylase, has been associated with induction of autophagy, reprogramming cellular metabolism, and regulating immune mediators. In this study, we investigated the role of SIRT1 in bone marrow dendrit...

Alternative Titles

Full title

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2377705357

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2377705357

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1008319

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