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Multimerization strategies for efficient production and purification of highly active synthetic cyto...

Multimerization strategies for efficient production and purification of highly active synthetic cyto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2385223873

Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands

About this item

Full title

Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-04, Vol.15 (4), p.e0230804-e0230804

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cytokine signaling is transmitted by cell surface receptors which act as natural biological switches to control cellular functions such as immune reactions. Recently, we have designed synthetic cytokine receptors (SyCyRs) consisting of green fluorescent protein (GFP)- and mCherry-nanobodies fused to the transmembrane and intracellular domains of cy...

Alternative Titles

Full title

Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2385223873

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2385223873

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0230804

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