Hexokinase II may be dispensable for CD4 T cell responses against a virus infection
Hexokinase II may be dispensable for CD4 T cell responses against a virus infection
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Activation of CD4 T cells leads to their metabolic reprogramming which includes enhanced glycolysis, catalyzed through hexokinase enzymes. Studies in some systems indicate that the HK2 isoform is the most up regulated isoform in activated T cells and in this report the relevance of this finding is evaluated in an infectious disease model. Genetic a...
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Full title
Hexokinase II may be dispensable for CD4 T cell responses against a virus infection
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TN_cdi_plos_journals_2390619352
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2390619352
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0191533
