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Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy ca...

Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy ca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2390637593

Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy capacity and hippocampal volume

About this item

Full title

Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy capacity and hippocampal volume

Publisher

United States: Public Library of Science

Journal title

PloS one, 2020-04, Vol.15 (4), p.e0231765-e0231765

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Non-invasive biomarkers will enable widespread screening and early diagnosis of Alzheimer's disease (AD). We hypothesized that the considerable loss of brain tissue in AD will result in detection of brain lipid components in urine, and that these will change in concert with CSF and brain biomarkers of AD. We examined urine dicarboxylic acids (DCA)...

Alternative Titles

Full title

Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy capacity and hippocampal volume

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2390637593

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2390637593

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0231765

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