STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency
STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency
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Author / Creator
Wang, Yuyan , Du, Shujuan , Zhu, Caixia , Wang, Chong , Yu, Nuoya , Lin, Ziqi , Gan, Jin , Guo, Yi , Huang, Xinxin , He, Yuping , Robertson, Erle , Qu, Di , Wei, Fang and Cai, Qiliang
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Latent Epstein-Barr virus (EBV) infection is strongly associated with several malignancies, including B-cell lymphomas and epithelial tumors. EBNA1 is a key antigen expressed in all EBV-associated tumors during latency that is required for maintenance of the EBV episome DNA and the regulation of viral gene transcription. However, the mechanism util...
Alternative Titles
Full title
STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency
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Record Identifier
TN_cdi_plos_journals_2390750186
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2390750186
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1008447
