Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene
Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The Ikzf1 locus encodes the lymphoid specific transcription factor Ikaros, which plays an essential role in both T and B cell differentiation, while deregulation or mutation of IKZF1/Ikzf1 is involved in leukemia. Tissue-specific and cell identity genes are usually associated with clusters of enhancers, also called super-enhancers, which are believ...
Alternative Titles
Full title
Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2406921536
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2406921536
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0233191
