Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations
About this item
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Author / Creator
Maes, Tamara , Mascaró, Cristina , Rotllant, David , Lufino, Michele Matteo Pio , Estiarte, Angels , Guibourt, Nathalie , Cavalcanti, Fernando , Griñan-Ferré, Christian , Pallàs, Mercè , Nadal, Roser , Armario, Antonio , Ferrer, Isidro , Ortega, Alberto , Valls, Nuria , Fyfe, Matthew , Martinell, Marc , Castro Palomino, Julio César and Buesa Arjol, Carlos
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Transcription disequilibria are characteristic of many neurodegenerative diseases. The activity-evoked transcription of immediate early genes (IEGs), important for neuronal plasticity, memory and behavior, is altered in CNS diseases and governed by epigenetic modulation. KDM1A, a histone 3 lysine 4 demethylase that forms part of transcription regul...
Alternative Titles
Full title
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations
Authors, Artists and Contributors
Author / Creator
Mascaró, Cristina
Rotllant, David
Lufino, Michele Matteo Pio
Estiarte, Angels
Guibourt, Nathalie
Cavalcanti, Fernando
Griñan-Ferré, Christian
Pallàs, Mercè
Nadal, Roser
Armario, Antonio
Ferrer, Isidro
Ortega, Alberto
Valls, Nuria
Fyfe, Matthew
Martinell, Marc
Castro Palomino, Julio César
Buesa Arjol, Carlos
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2407761470
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2407761470
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0233468
