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HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2434497646

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

About this item

Full title

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

Publisher

San Francisco: Public Library of Science

Journal title

PLoS pathogens, 2020-07, Vol.16 (7), p.e1008651-e1008651

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Type-2 immunity elicits tissue repair and homeostasis, however dysregulated type-2 responses cause aberrant tissue remodelling, as observed in asthma. Severe respiratory viral infections in infancy predispose to later asthma, however, the processes that mediate tissue damage-induced type-2 inflammation and the origins of airway remodelling remain i...

Alternative Titles

Full title

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2434497646

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2434497646

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1008651

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